Cdx2 expression and its promoter methylation during metaplasia-dysplasia-carcinoma sequence in Barre

• 作 者: Kenji Makita Riko Kitazawa Shu
• 机 构: DivisionofMolecularPathology,DivisionofPathology
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2013年4期
• 关键词: BARRETT ’s ESOPHAGUS CAUDAL type homebox transcription factor 2 Intestinal METAP
• 基金项目: Supported by Grant-in Aid from Ministry of Education,Sports and Culture (GP Program for Basic Science),Japan

AIM:To examine how the expression of caudal type homebox transcription factor 2(Cdx2) is regulated in the development of malignancy in Barrett’s esophagus.METHODS:Cdx2,mucin(MUC) series(MUC2,MUC5AC and MUC6),p53 and E-cadherin expression in Barrett’s esop