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用125I标记分析法对25例膀胱移行细胞癌组织和14例正常膀胱组织进行了EGF、EGFr含量测定。表明EGF、EGFr在肿瘤组织中的含量明显高于癌旁正常对照组织（P＜0.05）。肿瘤组织各病理分级组之间EGF、EGFr含量随病理分级增高，有明显增高趋势，但经统计学处理，尚未观察到有显著性差异（P＞0．05）。25例病人术后随访，1年内肿瘤复发的5例患者中，4例肿瘤组织中有EGFr较高水平的表达，表明EGFr与肿瘤复发有一定联系
Twenty-five cases of transitional cell carcinoma of the bladder and 14 cases of normal bladder tissue were assayed for EGF and EGFr by 125I labeling assay. The results showed that the content of EGF and EGFr in tumor tissue was significantly higher than that in adjacent normal tissues (P <0.05). The contents of EGF and EGFr increased with the pathological grade in the pathological grading groups of tumor tissues, which showed an obvious trend of increasing. However, there was no significant difference (P> 0.05) after statistical treatment. Of the 25 patients who were followed up for a period of 1 year, among the 5 patients who had tumor recurrence within one year, the high expression of EGFr was found in 4 of the tumor tissues, indicating that EGFr had a certain relationship with tumor recurrence