论文部分内容阅读
目的：探讨血浆内皮素水平与急性脑血管病的关系。方法：应用放射免疫分析法测定３６例脑出血、４０例脑梗塞及２１例蛛网膜下腔出血患者的血浆内皮素浓度。结果：三组脑血管病患者的血浆内皮素浓度均明显高于正常对照组（Ｐ＜０．０１），而三组急性脑血管病患者之间以蛛网膜下腔出血组最高，脑出血组次之，脑梗塞组较低。结论：提示内皮素参与急性脑血管病的病理生理过程，测定血浆内皮素浓度可作为急性脑血管病鉴别诊断的参考指标之一。
Objective: To investigate the relationship between plasma endothelin level and acute cerebrovascular disease. Methods: The plasma endothelin levels in 36 patients with cerebral hemorrhage, 40 with cerebral infarction and 21 with subarachnoid hemorrhage were determined by radioimmunoassay. Results: The plasma endothelin levels of three groups of patients with cerebrovascular disease were significantly higher than those of the normal control group (P <0.01), while those of the three groups of patients with acute cerebrovascular disease were the highest in the subarachnoid hemorrhage group and the cerebral hemorrhage group Second, lower cerebral infarction group. Conclusion: It is suggested that endothelin is involved in the pathophysiological process of acute cerebrovascular disease and determination of plasma endothelin concentration can be used as one of the reference indexes for the differential diagnosis of acute cerebrovascular disease.