论文部分内容阅读
回顾皮肌炎(DM)在南澳大利亚的流行情况,并分别与澳大利亚其他州及新西兰进行流行病学比较。通过肌肉活检和医院的分类资料获得在南澳大利亚、澳大利亚其他州和新西兰的皮肌炎患者的数据,研究环境因素在皮肌炎发病中的作用。自1990～2005年,经肌肉活检确诊的南澳大利亚皮肌炎患者21例(62%),平均年龄(49.7±18.4)岁,多发性肌炎(PM)患者99例,南澳大利亚地区,皮肌炎年平均发病率为1/100万,多发性肌炎年平均发病率为1/100万;自1991年在南澳大利亚医院有221例患者被诊断为皮肌炎和441例患者被诊断为多发性肌炎(PM)。DM/(DM+PM)比值被认为与日光照射有关,南澳大利亚地区该比值最低(0.39,95%CI:0.22～0.56),西澳大利亚地区该比值最高(0.67,95%CI:0.53～0.81),没有发现该比值与纬度、日照时间长短、云量、相对湿度及总降雨量相关。没有发现南澳大利亚地区该比值与社会经济地位相关。新西兰的数据和澳大利亚的数据相似,北岛和南岛DM/(DM+PM)比值分别是0.34和0.3。在南澳大利亚医院的分类资料反映了医院总的就诊患者,本研究从1997～2005年7月间没有被计入医院患者资料的DM/(DM+PM)比值,发现两者比值接近(0.38±0.08)。皮肌炎在炎症性肌炎中的相对比例随地区不同而有所差异,在南澳大利亚的值为:33%～38%。地理气候变量似乎不会影响澳大利亚皮肌炎与多发性肌炎的发病相对比率。
A review of the prevalence of dermatomyositis (DM) in South Australia and its epidemiological comparisons with other Australian states and New Zealand respectively. Dermatomyositis data from patients in South Australia, Australia and New Zealand were obtained from muscle biopsy and hospital classification data to investigate the role of environmental factors in the pathogenesis of dermatomyositis. Twenty-one patients (62%) with a mean age of 49.7 ± 18.4 years with polymyositis diagnosed by muscle biopsy from 1990 to 2005, 99 patients with polymyositis (PM), and South Australia, The average annual incidence of inflammation is 1 million, the average annual incidence of polymyositis is 1 million; since 1991 in South Australia Hospital, 221 patients were diagnosed with dermatomyositis and 441 patients were diagnosed as multiple Myositis (PM). The ratio of DM / (DM + PM) is considered to be related to daylight exposure, with the lowest in South Australia (0.39, 95% CI: 0.22-0.56) and the highest in Western Australia (0.67, 95% CI: 0.53-0.81) , No correlation was found between the ratio and latitude, duration of sunshine, cloud cover, relative humidity and total rainfall. The ratio in South Australia was not found to be related to socioeconomic status. New Zealand’s data are similar to those for Australia, with North / South DM / (DM + PM) ratios of 0.34 and 0.3, respectively. The classification data of hospitals in South Australia reflected the total number of patients in the hospital. The ratio of DM / (DM + PM), which was not included in the data of hospital patients from 1997 to July 2005, was found to be close to (0.38 ± 0.08). The relative proportion of dermatomyositis in inflammatory myositis varies from region to region, with a value of 33% to 38% in South Australia. Geographic variables do not seem to influence the relative incidence of dermatomyositis and polymyositis in Australia.