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目的:分析乳腺浸润性微乳头状癌(invasive micropapillary carcinoma,IMPC)的临床病理特征。方法:复习存档的乳腺癌病理切片,根据WHO分类标准,结合HE形态和免疫组化特征,诊断浸润性微乳头状癌6例,结合随访结果进行分析。结果:6例乳腺浸润性微乳头状癌中,淋巴结转移率为91.5%(86/94)。结论:乳腺浸润性微乳头状癌是一种少见类型的乳腺癌,具有侵袭性强、淋巴结转移率高、预后不良的生物学行为,无论肿瘤中IMPC结构比例占多少都应引起重视。
Objective: To analyze the clinicopathological features of invasive micropapillary carcinoma (IMPC). Methods: According to the WHO classification criteria and the morphological and immunohistochemical characteristics of HE, 6 cases of invasive papillary micro-carcinoma were diagnosed, and the results of follow-up were analyzed. Results: The lymph node metastasis rate was 91.5% (86/94) in 6 cases of invasive breast micro-papillary carcinoma. Conclusion: Breast invasive micropapillary carcinoma is a rare type of breast cancer with high aggressiveness, high lymph node metastasis rate and poor prognosis. No matter how much the proportion of IMPC structure in tumors should be taken seriously.