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铷(Rb)在细胞生物学的研究中,一直被用于钾(K)元素的替代元素,在一些报告中认为Rb的摄入与细胞中ATP的含量呈正成相关,对于乌本箭苷敏感的膜的离子通道不能区分Rb和K。尽管血清和一些生长因子都能显著地增加细胞对Rb和K的摄入,然而这一过程与DNA合成的增加无直接相关性,K在细胞质中是丙酮酸激酶的辅助因子,K能增加该酶的活性从而导致糖酵解过程的增强,并且在快速分裂的非肿瘤细胞的细胞核中K含量显著高于低速分裂细胞。与K不同,外加Rb能抑制动物肿瘤的增长。并且在流行病学的统计结果中发现高Rb营养地区癌症发病率低,胎儿组织中Rb含量高的地区癌症死亡率显著
Rubidium (Rb) has been used as an alternative element to potassium (K) elements in the study of cell biology. In some reports, Rb uptake is positively correlated with ATP content in cells and is sensitive to Of the ion channels of the membrane can not distinguish Rb and K. Although both serum and some growth factors significantly increase cellular uptake of Rb and K, there is no direct correlation between this process and an increase in DNA synthesis, and K is a cofactor for pyruvate kinase in the cytoplasm, with K increasing The activity of the enzyme thus leads to an enhancement of the glycolysis process, and the K content in the rapidly dividing non-tumor cell nucleus is significantly higher than that in the low-speed dividing cells. Unlike K, the addition of Rb inhibits tumor growth in animals. And in the epidemiological findings found in high Rb nutrition area cancer incidence is low, high fetal Rb content cancer mortality was significantly