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艾滋病是由艾滋病病毒引起的一种传染病。传播快,发病率、死亡率高。近年来临床上应用抗艾滋病药物,取得一些进展,现报告如下:1 沙利度胺 美国Celgene公司和美国国产过敏性和传染性疾病研究所(NIAID)称已达成协议,通过临床试验评价沙利度胺(thalidomide,Synovir)对HIV阳性病人的的效果。临床前研究表明,沙利度胺可选择性地抑制肿瘤坏死因子(TNF)a,据认为该细胞活素是一种HIV复制的强活化剂。在17名患进行性HIV-1
AIDS is an infectious disease caused by the AIDS virus. Spread fast, morbidity, high mortality. In recent years, clinical application of anti-AIDS drugs, made some progress, are as follows: 1 Thalidomide United States Celgene and the United States Institute of Allergy and Infectious Diseases (NIAID) said it has reached an agreement to evaluate the clinical trials of thalidomide Effect of thalidomide (Synovir) on HIV-positive patients. Preclinical studies have shown that thalidomide selectively inhibits tumor necrosis factor (TNF) a, which is thought to be a strong activator of HIV replication. In 17 patients with progressive HIV-1