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目的探讨输卵管妊娠保守性手术同时行妊娠黄体剥除对持续性异位妊娠发生的影响。方法选择2008年2月-2013年2月258例输卵管妊娠保守性手术患者,130例(A组)术中同时剥除妊娠黄体,128例(B组)未行妊娠黄体剥除,研究两种手术的治疗效果。结果 A组术后持续性异位妊娠发生率1.54%(2/130),显著低于B组10.16%(13/128),差异有统计学意义(P<0.05),术后选择天花粉蛋白注射治疗持续性异位妊娠均获得成功。结论输卵管妊娠保守性手术的同时行妊娠黄体剥除,对预防持续性异位妊娠的发生有明显作用,天花粉蛋白杀灭残余滋养细胞效果肯定,血β-hCG下降迅速,副作用小。
Objective To investigate the effect of conservative surgery of tubal pregnancy on the incidence of persistent ectopic pregnancy with luteal eradication. Methods From February 2008 to February 2013, 258 patients with conservative treatment of tubal pregnancy were enrolled in the study. One hundred and thirty patients (group A) underwent simultaneous removal of pregnant corpus luteum during operation and 128 patients (group B) Therapeutic effect of surgery. Results The incidence of persistent ectopic pregnancy in group A was 1.54% (2/130), significantly lower than that in group B (10.16%, 13/128) (P <0.05) Treatment of persistent ectopic pregnancy have been successful. Conclusions Simultaneous tubal luteal removal during conservative surgery of tubal pregnancy has a significant effect on the prevention of persistent ectopic pregnancy. Trichosanthin is effective in killing residual trophoblast cells, and the blood β-hCG is rapidly decreased with fewer side effects.