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目的探讨糖化血红蛋白HbA1c水平与冠状动脉病变严重程度的相关关系。方法随机选取2013年1月~2015年1月来我院心血管内科住院并进行选择性冠脉造影(CAG)的96例患者,分为冠心病组(56例)和对照组(40例),对这96例患者进行糖化血红蛋白测定,回顾性分析冠心病患者的临床症状、体征、诊疗等相关指标,以了解HbA1c水平与冠状动脉病变程度的关系。结果对冠心病患者进行临床调查,并对结果进行记录,冠心病组和对照组HbA1c水平比较可知,冠心病组HbA1c水平高于正常对照组(P﹤0.05)。结论对冠心病患者进行糖化血红蛋白水平检测,严格控制高血糖,降低HbA1c水平,通过改善血管内皮细胞功能,对延缓或阻止动脉粥样硬化,减少心血管并发症和后遗症的发生有着重要意义。
Objective To investigate the relationship between the HbA1c level and the severity of coronary artery disease. Methods 96 patients with coronary artery disease (CAG) hospitalized in our hospital from January 2013 to January 2015 were randomly divided into coronary heart disease (56 cases) and control group (40 cases) , The 96 cases of patients with glycated hemoglobin determination, retrospective analysis of clinical symptoms, signs, diagnosis and treatment of coronary heart disease and other related indicators in order to understand the relationship between the level of HbA1c and coronary artery disease. Results The clinical investigation of patients with coronary heart disease, and the results were recorded, coronary heart disease group and control group HbA1c level comparison shows that coronary heart disease group HbA1c levels were higher than the normal control group (P <0.05). Conclusions The detection of HbA1c in patients with coronary heart disease, strict control of hyperglycemia, reduce the level of HbA1c, by improving the function of vascular endothelial cells on the delay or prevent atherosclerosis and reduce cardiovascular complications and the occurrence of sequelae is of great significance.