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应用四甲基偶氮唑盐(MTT)法检测了31例未经治疗的囊虫病患者外周血单个核细胞(PBMC)产生IL-2水平,同时用ELISA双抗体夹心法测定其血清中sIL-2R水平,以30例健康人作对照。实验结果显示,囊虫病患者PBMC产生IL-2水平明显低于正常人(P<0.05),而患者血清中sIL-2R水平明显高于正常人(P<0.01)。本实验提示囊虫病患者外周血中低水平的IL-2及血清中高水平的sIL-2R可能与患者细胞免疫功能低下有关。
The levels of IL-2 in peripheral blood mononuclear cells (PBMCs) from 31 patients with untreated cysticercosis were detected by MTT assay. Meanwhile, the levels of sIL -2R levels to 30 healthy people as a control. The results showed that the level of IL-2 in PBMC of patients with cysticercosis was significantly lower than that of normal people (P <0.05), while the serum level of sIL-2R in patients with cysticercosis was significantly higher than that of normal people (P <0.01). This experiment suggests that low levels of IL-2 in peripheral blood of patients with cysticercosis and high levels of serum sIL-2R may be related to patients with cellular immune dysfunction.