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用抗癌药丝裂霉素Ｃ给小鼠腹腔内注射，同时口服中成药紫华荣及其主要成分紫草根、黄芪、川芎，以探讨中药对小鼠巨噬细胞和淋巴细胞的影响。结果丝裂霉素Ｃ能使小鼠腹腔内巨噬细胞数量减少，向异物的游走能力减慢，脾脏重量减轻，Ｔ淋巴细胞的母细胞化能力下降以及ＮＫ细胞的细胞毒作用减弱，并对巨噬细胞、Ｔ淋巴细胞的损害有防御作用。提示：紫华荣不但能刺激网状内皮系统使抑制状态的巨噬细胞恢复活性，也能使抑制的淋巴细胞活跃，对丝裂霉素Ｃ所造成的免疫不全现象起到积极的防御作用。
The mice were intraperitoneally injected with the anticancer drug mitomycin C, and the Chinese patent medicine Zihuarong and its main components Lithospermum erythropolis, Astragalus membranaceus and Rhizoma Chuanxiong were taken orally to investigate the effects of Chinese herbs on mouse macrophages and lymphocytes. RESULTS: Mitomycin C reduced the number of macrophages in the peritoneal cavity of mice, slowed migration to foreign bodies, reduced spleen weight, decreased the ability of T lymphocyte cell maturation, and decreased cytotoxicity of NK cells. It has a defensive effect on the damage of macrophages and T lymphocytes. Tip: Zihua Rong can not only stimulate the reticuloendothelial system to restore the activity of macrophages in the inhibitory state, but also activate the inhibited lymphocytes and play a positive defense role against the immune incompleteness caused by mitomycin C.