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目的评价埃索美拉唑联合莫沙必利治疗反流性食管炎的临床效果。方法选择82例反流性食管炎患者,随机分为两组,治疗组给予埃索美拉唑联合莫沙必利,对照组给予莫沙必利。观察4、8周的临床症状改善和8周后的内镜下变化情况。结果两组疗效、内镜检查比较差异有显著性(P<0.05)。结论埃索美拉唑联合莫沙必利治疗返流性食管炎较单独用药疗效显著。
Objective To evaluate the clinical efficacy of esomeprazole combined with mosapride in the treatment of reflux esophagitis. Methods 82 patients with reflux esophagitis were randomly divided into two groups. The treatment group was given esomeprazole combined with mosapride and the control group was given mosapride. The improvement of clinical symptoms at 4 and 8 weeks and the endoscopic changes after 8 weeks were observed. Results The efficacy of the two groups, endoscopy showed significant difference (P <0.05). Conclusion Esomeprazole combined with mosapride in the treatment of reflux esophagitis was more effective than single drug therapy.