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目的调查分析河北省任县干部职工血脂异常与并发症发病情况,为制定其预防与控制措施提供依据。方法以河北省任县2 668人在职和离退休干部职工为调查对象,对高血脂、高血压、高血糖、超重与肥胖、颈动脉脂质沉积、脂肪肝、眼睑黄色瘤、脑梗死患病情况和放置冠脉支架情况进行流行病学调查。结果在2 668名被调查者中,男性血脂异常标化患病率高于女性,差异有统计学意义(χ2=16.33,P<0.01)。在男性血脂异常患者中,20～29、30～39岁、40～49岁年龄段血脂异常患病率明显高于女性,差异有统计学意义(χ2=19.89、16.68、11.22,P<0.01)。在50岁以后,男女血脂异常患病率的差异无统计学意义(χ2=1.23、2.36,P>0.05)。在血脂异常患者中,常见的慢性并发症高血压、高血糖、超重与肥胖、颈动脉脂质沉积、脂肪肝、眼睑黄色瘤、脑梗死和放置冠脉支架者明显高于血脂正常者,差异均有统计学意义(χ2=98.69、92.23、92.83、187.57、162.32、67.88、12.65、13.96,P<0.01)。结论该县干部职工血脂异常患病率较高,血脂异常与眼睑黄色瘤、心脑血管疾病以及糖尿病等慢性疾病的患病率有关。
Objective To investigate and analyze the incidence of dyslipidemia and complication among cadres and workers in Renxian County, Hebei Province, and to provide the basis for formulating their prevention and control measures. Methods A total of 2 668 serving and retired cadres and workers in Renxian County, Hebei Province, were enrolled in this study. The effects of hyperlipidemia, hypertension, hyperglycemia, overweight and obesity, carotid artery lipid deposition, fatty liver, eyelid xanthomas, Epidemiological investigation of the situation and placement of coronary stents. Results Among 2 668 respondents, the prevalence of dyslipidemia was higher in males than in females (χ2 = 16.33, P <0.01). Among the male patients with dyslipidemia, the prevalence of dyslipidemia in 20-29, 30-39 and 40-49 age groups was significantly higher than that in women (χ2 = 19.89, 16.68, 11.22, P <0.01) . There was no significant difference in the prevalence of dyslipidemia between men and women after age 50 (χ2 = 1.23, 2.36, P> 0.05). In patients with dyslipidemia, the common chronic complications of hypertension, hyperglycemia, overweight and obesity, carotid artery lipid deposition, fatty liver, eyelid yellow tumor, cerebral infarction and coronary stent were significantly higher than those with normal blood lipids, the difference (Χ2 = 98.69,92.23,92.83,187.57,162.32,67.88,12.65,13.96, P <0.01). Conclusion The prevalence of dyslipidemia among cadres and workers in this county is high. The prevalence of dyslipidemia is related to the prevalence of chronic diseases such as eyelid xanthomas, cardiovascular and cerebrovascular diseases and diabetes mellitus.