Optimization of Ultrasonic Extraction Process of Glycyrrhizic Acid and Liquiritin from Extractum Gly

• 作 者: Huihui SHEN Xianglin ZHANG Fei LI Shiyu LI
• 机 构: Inspection and Quarantine Technique Center of Xinjiang Entry-Exit Inspection and Quarantine Bureau,A
• 出 处: Medicinal Plant
• 发表日期: 2016年Z5期
• 关键词: ultrasonic technological ethanol optimize ammonium extremely declined fitting ba

[Objectives] To optimize the extraction technique for glycyrrhizic acid and liquiritin from Xinjiang extractum glycyrrhizae by response surface method. [Methods] Based on the single-factor tests on ethanol concentration,ultrasonic wave time and solid-liquid ratio,response surface method of three factors and three levels was adopted according to the Box-Behnken central composite design principle. The technological condition of glycyrrhizic acid and liquiritin was optimized by ultrasonic wave. [Results]The optimal extraction process for glycyrrhizic acid and liquiritin was as follows: 60 % ethanol concentration,30 min ultrasonic time,2. 6 g/L solid-liquid ratio. Under these conditions,the one-time extraction rate of glycyrrhizic acid and liquiritin was 8. 12 % and 0. 736 %,respectively. [Conclusions]The optimal extraction technology for glycyrrhizic acid and liquiritin from extractum glycyrrhizae was established,which could provide theoretical foundation for the intensive processing of extract and the application of glycyrrhizic acid and liquiritin in food and medicine.

[Objectives] To optimize the extraction technique for glycyrrhizic acid and liquiritin from Xinjiang extractum glycyrrhizae by response surface method. [Methods] Based on the single-factor tests on ethanol concentration, ultrasonic wave time and solid-liquid ratio, response surface method of three Factors and three levels was adopted according to the Box-Behnken central composite design principle. The technological condition of glycyrrhizic acid and liquiritin was optimized by ultrasonic wave. [Results] The optimal extraction process for glycyrrhizic acid and liquiritin was as follows: 60% ethanol concentration, 30 min ultrasonic time, 2.6 g / L solid-liquid ratio. Under these conditions, the one-time extraction rate of glycyrrhizic acid and liquiritin was 8. 12% and 0. 736%, respectively. [Conclusions] The optimal extraction technology for glycyrrhizic acid and liquiritin from extractum glycyrrhizae was established, which could provide theoretical foundation for the intensive processing of e xtract and the application of glycyrrhizic acid and liquiritin in food and medicine.