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神经鞘瘤是来源于神经髓鞘的良性肿瘤,多见于头颈部软组织。骨内神经鞘瘤较为罕见,但以下颌骨相对常见。本文报告1例首发表现为下颌下肿块的下颌骨多发性骨内神经鞘瘤,详细描述其临床特征、影像学表现、手术所见、病理结果以及术后随访情况,并回顾国内外文献将其好发因素、临床表现、影像学表现、组织病理学表现以及治疗情况和预后作了系统性总结和分析。大多数骨内神经鞘瘤临床表现一般为进行性无症状性下颌骨膨胀,也可表现为颌面畸形、牙移位或拥挤。
Schwannoma is a benign tumor derived from myelin sheath, more common in head and neck soft tissue. Bone schwannoma is relatively rare, but the following jaw is relatively common. This article reports a case of multiple mandibular multiple schwannoma of the mandible with first submandibular mass. The clinical features, imaging findings, surgical findings, pathological findings and postoperative follow-up were described in detail. The main factors, clinical manifestations, imaging findings, histopathological findings and treatment and prognosis were systematically summarized and analyzed. Most of the clinical manifestations of intraosseous nerve sheath tumors are generally progressive asymptomatic mandibular expansion, but also showed maxillofacial deformity, tooth displacement or crowding.