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目的研究肌钙蛋白Ⅰ(cTnⅠ)检测在病毒性心肌炎(VMC)中的临床应用价值,并与常规检测项目肌酸激酶同工酶(CK-MB)进行比较,为VMC的诊断提供较好的指标。方法对临床确诊的60例VMC患儿,在不同的时间段进行上述两项指标的检测,并与60例健康人的检测结果进行比较。结果 60例患儿的CK-MB在VMC起病后8～12h开始升高,24～48h达到高峰;cTnⅠ在VMC起病后4～6h开始升高,12～24h达到高峰;两项指标高峰值与对照组比较差异均有统计学意义。结论 CK-MB作为早期诊断指标欠佳,cTnⅠ可作为VMC早期诊断的较好指标。
Objective To investigate the clinical value of cTnI detection in viral myocarditis (VMC) and to compare with CK-MB in routine test to provide better diagnostic value for VMC index. Methods 60 cases of VMC clinically diagnosed in children at different time intervals for the detection of the above two indicators, and with 60 healthy people test results were compared. Results The CK-MB in 60 children started to increase from 8 to 12 hours after onset of VMC and peaked from 24 to 48 hours. The cTnⅠ level increased from 4 to 6 hours after onset of VMC and reached the peak from 12 to 24 hours. The peak of two indexes The difference between the control group and the control group was statistically significant. Conclusion CK-MB as an indicator of early diagnosis is poor, cTn Ⅰ can be used as a good indicator of early diagnosis of VMC.