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For the first time,prevention and treatment of senile disease was listed in National Key Projects after repeated provement among specialists during “ Nine Five ” phase,which promotes development of senile health work. Diabetes,osteoporosis,Parkinsons disease and senile dementia are frequently encountered diseases among elders.There conditions are not leading causes of death,but they consumed a lot of medical resource.Complications and higher disbility rate seriously endanger elders quality of life and increase family and social load.There senile diseases will affect continued development of our economy without appropriate prevention and treatment. Using same project and standard,multicenter study on diabetes mellitus,essential osteoporosis,senile dementia,Parkinson disease was conducted through multiple layer and phase chester sampling method. Pvevalence,risk factors associated with these disease were investigated.Sex,age,education level and prevalence in town and country were compared.Based on previous job,IGT was used to decrease community intervention.Test communities for prevention and treatment of senile disease such as diabetes mellitus,essential osteoporosis,senile dementia,Parkinson disease were established.