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糖尿病肾病(DN)是一常见的糖尿病慢性并发症,是糖尿病患者死亡的主要原因之一。ZATZ等报告在糖尿病动物限制蛋白质摄入量,可防止肾脏损伤与肾小球压力上升。本研究旨在观察低蛋白饮食对早期DN患者肾功能及营养状态的影响。1 临床资料1.1 对象和方法:受试对象为29例按WHO糖尿病诊断标准诊断的NIDDM患者,无高血压、尿路感染、肾炎、心衰等可引起尿白蛋白增高的因素。用放射免疫法测尿白蛋白排出
Diabetic nephropathy (DN) is a common chronic complication of diabetes and is one of the major causes of death in diabetic patients. ZATZ and other reports limit protein intake in diabetic animals to prevent kidney damage and glomerular pressure rise. This study aimed to observe the effects of low-protein diet on renal function and nutritional status in patients with early DN. 1 Clinical data 1.1 Subjects and Methods: The subjects were 29 cases of NIDDM diagnosed according to WHO diagnostic criteria for diabetes, hypertension, urinary tract infections, nephritis, heart failure and other factors that can cause elevated urinary albumin. Urinary albumin excretion was measured by radioimmunoassay