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本文通过离体的血凝块，进行实验研究观察尿激酶药物的纤溶效果、溶解时间及最低有效浓度。采用ＣＴ引导立体定向血肿排空治疗老年高血压脑出血５０例。血肿位于壳核２４例，丘脑１６例，皮层下８例，小脑２例。除小脑血肿＜１３ｍｌ外，２０～６０ｍｌ４４例，６０ｍｌ以上４例。６例血肿呈液状一次除净，４４例呈凝血块均行碎化抽吸清除。清除量＞７０％２４例，５０～７０％２０例，３０例加用尿激酶治疗。手术死亡率４％，４８例术后随访３个月（以ＡＤＬ为标准），１级１３例（２７％），２级２３例（４８％），３级１０例（２１％），４级２例（４．２％）。
In this paper, through ex vivo clots, experimental study of urokinase fibrinolytic effect, dissolution time and the lowest effective concentration. Fifty patients with senile hypertensive intracerebral hemorrhage were treated with CT guided stereotactic hematoma evacuation. Hematoma in the putamen 24 cases, 16 cases of thalamus, cortex in 8 cases, 2 cases of cerebellum. In addition to cerebellar hematoma <13ml, 20 ~ 60ml44 cases, 60ml above 4 cases. Six cases of hematoma were liquid in addition to a net, 44 cases were coagulation clotting removal clearance. Clearance> 70% in 24 cases, 50% to 70% in 20 cases, 30 cases plus urokinase treatment. Surgical mortality was 4%, 48 cases were followed up for 3 months (ADL as the standard), grade 1 in 13 cases (27%), grade 2 in 23 cases (48%), grade 3 in 10 cases (21% 2 cases (4.2%).