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实体肿瘤的生长和转移与肿瘤内微血管生成的数量有关,而肝细胞生长因子(HGF)和c-Met基因产物的活性和/或表达又与胚胎发生,器官进化,血管生成及增生活动有关。为评价肿瘤血管生成、HGF和c-Met在子宫内膜癌预后中的意义,选择93例子宫内膜癌患者,均来自1991～1995年间东京大学附属医院,平均年龄56岁,93例FIGO分期Ⅰ+Ⅱ期65例,Ⅲ+Ⅳ期28例,组织学分级44例G_1级,29例G_2级,20例G_3级22例淋巴结阳性,64例肌
The growth and metastasis of solid tumors are related to the amount of intratumoral angiogenesis, whereas the activity and / or expression of hepatocyte growth factor (HGF) and c-Met gene products are in turn related to embryogenesis, organ evolution, angiogenesis, and proliferative activity. To evaluate the significance of tumor angiogenesis, HGF and c-Met in the prognosis of endometrial cancer, 93 patients with endometrial cancer were selected from the University Hospital of Tokyo from 1991 to 1995 with a mean age of 56 years and 93 cases of FIGO stage There were 65 cases of stage Ⅰ + Ⅱ and 28 cases of stage Ⅲ + Ⅳ. There were 44 cases of G_1, 29 cases of G_2, 20 cases of G_3, 22 cases of lymph node positive, 64 cases of muscle