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目的探讨不同术式对胃癌穿孔治疗的临床疗效。方法 2006年9月~2009年9月期间,某院诊治的90例胃癌穿孔患者,根据术式分为穿孔修补术组、姑息性切除术组和根治性切除术组,每组各30例,对比其手术疗效。结果术后随访2~5年。与穿孔修补术相比,姑息性切除和根治性切除术的死亡率和并发症明显降低,P﹤0.05,差异有统计学意义;与穿孔修补术组相比,姑息性切除术组和根治性切除术组的生存期明显延长,P﹤0.05,差异有统计学意义;与姑息性切除术相比(580.3±35.1)d,根治性切除术组的生存期明显延长(770.6±46.2)d,P﹤0.05,差异有统计学意义。结论姑息性切除术和根治性切除术,都可以明显延长胃癌穿孔患者的生存期,根治性切除术是唯一可能治愈胃癌的手术方式。
Objective To investigate the clinical effects of different surgical procedures on perforation of gastric cancer. Methods From September 2006 to September 2009, 90 patients with gastric perforation who were diagnosed and treated in a hospital were divided into perforation repair group, palliative resection group and radical resection group according to the surgical procedure, 30 cases in each group, Contrast its surgical efficacy. Results The patients were followed up for 2 to 5 years. Compared with the perforation repair, the mortality and complications of palliative resection and radical resection were significantly reduced, P <0.05, the difference was statistically significant; compared with the perforation repair group, palliative resection group and radical Survival of the resection group was significantly prolonged, P <0.05, the difference was statistically significant; compared with palliative resection (580.3 ± 35.1) d, radical resection group survival was significantly longer (770.6 ± 46.2) d, P <0.05, the difference was statistically significant. Conclusions Both palliative resection and radical resection can significantly prolong the survival of patients with gastric cancer perforation. Radical resection is the only surgical approach that may cure gastric cancer.