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研究了meso－四（对－三甲基氨基本基）卟啉（TAPP）和meso－四（对－甲基吡啶基）卟啉（TMPyP－4）与核酸作用的电子吸收光谱、荧光光谱和共振光散射光谱的特性．电子吸收和荧光光谱研究表明，这两个水溶性阳离子卟啉与核酸的摩尔比（R）大于0．25时，核酸对卟啉的Soret带都有减色效应和荧光碎灭效应；当R＜0．25时，核酸与卟啉作用形成新的荧光复合物．共振光散射光谱研究表明，核酸使TAPP的共振光散射增强，但对TMyyP－4的共振光散射信号无影响．
The electron absorption and fluorescence spectra of meso-tetrakis (p-trimethylaminomethyl) porphyrin (TAPP) and meso-tetrakis (p-methylpyridyl) porphyrin (TMPyP-4) Resonance light scattering properties of the spectrum. The results of electron absorption and fluorescence spectroscopy showed that when the molar ratio (R) of these two water-soluble cationic porphyrins to the nucleic acid was greater than 0.25, the nucleic acid had a hypochromic effect and a fluorescence quenching effect on the Soret band of porphyrin. When R <0.25, the nucleic acid and porphyrin to form a new fluorescence complex. Resonance light scattering spectroscopy showed that the nucleic acid enhanced the resonance light scattering of TAPP, but had no effect on the resonance light scattering signal of TMyyP-4.