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子宫内膜异位症(endometriosis,EM)是导致生育年龄妇女不孕的常见原因之一,其对生育能力的影响是多方面的,其中卵泡发育异常卵母细胞质量下降是导致不孕的主要原因之一。卵母细胞的质量决定卵细胞的发育,胚胎的发育潜能。EM患者卵泡发育潜能下降、卵泡液微环境、抑制素的改变,都会对卵子造成损害。现就这几方面进行综述,为在临床工作中改善EM患者卵细胞质量提供理论依据。
Endometriosis (EM) is one of the most common causes of infertility in women of childbearing age. The effects of endometriosis on fertility are multifarious. The decline of follicular oocyte quality is the main cause of infertility one of the reasons. The quality of the oocyte determines the development of the egg cell and the developmental potential of the embryo. EM patients with follicular development potential decline, follicular fluid microenvironment, inhibin changes, will cause damage to the egg. Now on these aspects are reviewed, in order to provide a theoretical basis for improving the quality of egg cells in patients with EM in clinical work.