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为了探讨三叉初级传入路径中传导伤害性信息的小神经元在结构和功能上的差异，用植物凝集素（Ｂａｎｄｅｉｒａｅａｓｉｍｐｌｉｃｉｆｏｌｉａｉｓｏｌｅｃｔｉｎ－Ｂ４，ＢＳＩ－Ｂ４）法在光镜、电镜水平观察了三叉初级传入路径中标记神经元的分布及形态特征。光镜结果表明：ＢＳＩ－Ｂ４标记的初级传入终末只分布于三叉神经尾侧亚核的Ⅰ层和Ⅱ层，尤以Ⅱ层密集，标记终末光滑不呈串珠状。三叉神经节中的ＢＳＩ－Ｂ４标记神经元为中小型神经元，其中以小神经元为主。电镜观察表明：ＢＳＩ－Ｂ４只标记无髓纤维，不标记有髓纤维；ＢＳＩ－Ｂ４标记的轴突终末与阴性树突形成非对称性的轴树突触，突触小泡多为圆形清亮小泡，偶见大致密核心囊泡。提示：传导伤害性信息的三叉初级感觉神经元中，ＢＳＩ－Ｂ４标记的神经元和Ｐ物质（ＳＰ）能神经元在功能上有明显差异，而标记神经元和谷氨酸能神经元可能具有类似的功能
To investigate the differences in structure and function of small neurons that conduct damage information in the trifurcation primary pathway, the primary trigeminal afferent pathway was observed under light and electron microscopy using the plant lectin (Bandeiraeasimplicifolia isolectin-B4, BSI-B4) Marked in the path of neuronal distribution and morphological characteristics. The results of light microscopy showed that the primary afferent terminal of BSI-B4 was only distributed in the first and second layers of the subnucleus of the trigeminal nerve, especially in the second layer. The terminal end of the marker was smooth and not beaded. BSI-B4 labeled neurons in the trigeminal ganglion were small and medium sized neurons, of which small neurons were dominant. Electron microscopy showed: BSI-B4 only labeled non-myelinated fibers, not labeled with myelinated fibers; BSI-B4-labeled axon terminals and negative dendrites form asymmetric axonal synapses, mostly synaptic vesicles Clear vesicles, occasionally roughly dense core vesicles. TIP: Among the trigeminal primary sensory neurons that transduce harmful information, BSI-B4 labeled neurons and substance P (SP) competent neurons have significant functional differences, whereas labeled neurons and glutamatergic neurons may have Similar function