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目的：对人工全膝关节表面置换治疗骨性膝关节炎进行分析。方法选取典型的骨性膝关节炎患者59例，其中男性10例，女性49例。左膝有14例，右膝有25例，双膝有25例，对这些患者都进行人工全膝关节的表面置换。结果所选59例患者都成功完成置换，随访期为18个月。84膝在置换12w以后，膝评分是（90.9±11.8）分，功能评分是（87.9±10.9）分，都比置换以前的（47.5±6.2）分及（51.3±7.8）分显著高。结论对骨性膝关节炎患者进行人工全膝关节表面置换治疗，可以获得较好的治疗效果，并改善患者的膝关节功能。“,”Objective To analyze the ef icacy of total knee replacement (TKR) in treating osteoarthritis. Methods Fifty-nine osteoarthritis patients were selected, including 10 males and 49 females. There were 14 cases af ected left knees, 20 af ected right, and 25 bilateral. Al patients underwent TKR. Result The operation was successful y performed in 59 patients. They were al fol owed up for 18 months meanly. The knee Scores was 47.5±6.2 preoperatively and 90.9±11.8 at the twelfth postoperative week, and the value of the functional scores was51.3 ±7.8 preoperatively and 87.9 ±10.9 at the twelfth postoperative week. Conclusion TKR can greatly improve knee joint function in treating osteoarthritis.