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近来,采用Okamato引物对或者是Takasashi引物对作聚合酶链反应(PCR),在具有或不具有输血史及肝病病史儿童中调查TT病毒(TTV)DNA流行率的研究较多。在具有输血史儿童(包括恶性病及非恶性病人群)中,采用Okamato及Takasashi引物测得阳性率分别为31.6％(12/38)和78.9％(30/38);而在未曾输血儿童中,则分别为6.7％(2/30)和60％(18/30)。另一方面,在B型肝炎患者中,这一流行率分别为0％(0/16)和50％(8/16);在C型肝炎患者中,其值分别为21.4％(3/14)和71.4％(10/14);而在非A-C型肝炎患者(含27例急性肝炎病人,5例爆发
Recently, there have been many studies investigating the prevalence of TT virus (TTV) DNA in children with or without transfusion history and liver disease using the Okamato primer pair or Takasashi primer pair for polymerase chain reaction (PCR). The positive rates of Okamato and Takasashi primers were 31.6% (12/38) and 78.9% (30/38) respectively in children with transfusion history (including malignant and non-malignant patients), while in non-transfused children , Respectively, 6.7% (2/30) and 60% (18/30) respectively. On the other hand, the prevalence in patients with hepatitis B was 0% (0/16) and 50% (8/16), respectively; in patients with hepatitis C, the prevalence was 21.4% (3/14 ) And 71.4% (10/14) respectively. However, in non-AC hepatitis patients (including 27 cases of acute hepatitis, 5 cases of outbreaks