论文部分内容阅读
目的 探讨脊髓型多发性硬化 (MS)的临床和影像学特点及其诊断意义。方法 对 2 2例脊髓型 MS的临床特点和磁共振 (MRI)结果进行回顾性分析。结果 脊髓型 MS,占同期 MS住院患者的 1 1 .8%。女性比例较高 ,多见于中年发病 ,常以急性或亚急性起病 ,表现为复发 -缓解或慢性进展病程 ,最常累及中高位颈髓和中段胸髓 ,大多复发仍局限于原发部位。MRI特点为髓内散在的长 T1、长 T2斑块状病灶 ,其长度一般小于 2个椎体的长度 ,位于脊髓的后外侧 ,面积小于脊髓横截面的 1 /2。应用糖皮质激素试验性治疗对诊断 ,尤其是对首次发病时脊髓出现可疑脱髓鞘病灶者诊断有一定帮助。结论 诊断脊髓型 MS主要依据其临床表现 ,MRI为最敏感的检查方法 ,激素试验性治疗有时是必要的。
Objective To investigate the clinical and imaging features of spinal cord multiple sclerosis (MS) and their diagnostic significance. Methods The clinical features and magnetic resonance imaging (MRI) findings of 22 cases of spinal cord MS were retrospectively analyzed. Results Spinal cord MS, accounting for 11.8% of MS patients in the same period. A higher proportion of women, more common in middle age, often acute or subacute onset, manifested as recurrence - the course of disease or chronic progression, most commonly involving the middle and high cervical cord and the middle of the chest, most of the recurrence is still confined to the primary site . MRI features intramedullary scattered long T1, long T2 plaque lesions, its length is generally less than 2 vertebral length, located in the posterior lateral spinal cord, the area is less than 1/2 of the spinal cord cross-section. The experimental treatment of glucocorticoid is useful for the diagnosis of the diagnosis, especially for the diagnosis of suspected demyelinating lesions in the first episode of spinal cord. Conclusion The diagnosis of spinal cord MS mainly based on its clinical manifestations, MRI is the most sensitive method of examination, hormone therapy is sometimes necessary.