Hepatic adenomatosis associated with hormone replacement therapy and hemosiderosis: A case report

• 作 者: Satoshi Hagiwara Hitoshi Takagi Daisuke Kanda Naondo Sohara Satoru Kakizaki Kenji Katakai Teruo Yoshinaga Tsugio Higuchi Kenichi Nomoto Hiroyuki Kuwano Masatomo Mori
• 机 构: Saiseikai Maebashi Hospital, 564-1 Kamishinden, Maebashi, Gunma 371-0821, Japan“,”Department of Medi
• 出 处: 世界胃肠病学杂志（英文版）
• 发表日期: 2006年4期
• 关键词: Hepatic adenomatosis Estrogen Iron overload

We have reported a case of hepatic adenomatosis associated with hormone replacement therapy (estrogen and progesterone) and hemosiderosis caused by excessive blood transfusion for the treatment of chronic myeloid leukemia. A 34-year-old woman was found to have several hepatic tumors on a routine medical examination. The general condition was good.Laboratory studies showed iron overload. Abdominal computed tomography and selective hepatic angiography showed several hypervascular tumors in the right lobe of the liver (up to 20 mm in diameter). Since hepatocellular carcinoma could not be ruled out, subsegmental hepatectomy was performed. Histopathological examination of the surgical specimen showed hepatic adenomatosis with hemosiderosis. Both hormone replacement therapy and iron overload could be the cause of hepatic adenomatosis.