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目的研究原发性开角型青光眼(POAG)、正常眼压性青光眼(NTG)患者及正常人双眼眼压昼夜波动趋势及其眼压峰值出现的规律,比较双眼眼压波动趋势是否一致。设计前瞻性病例系列。研究对象POAG、NTG患者及正常对照各30例。方法用Goldmann压平眼压计测量眼压日曲线,比较双眼的日眼压波动模式及眼压峰值分布。主要指标眼压测量值。结果眼压峰值出现于非办公时段的正常人为右眼6．7%、左眼10．0%;NTG患者为右眼20．0%、左眼23．3%;POAG患者为右眼23．3%、左眼20．0%。结论POAG、NTG患者和正常人有着不同的眼压昼夜波动模式,且双眼的波动趋势不尽相同,不能完全将双眼等同看待;部分观察对象的峰值眼压分布于非办公时段,办公时段多次眼压测量不能完全代替一日眼压监测。(眼科,2007,16:33-36)
Objective To investigate the diurnal fluctuation of intraocular pressure (IOP) and the occurrence of intraocular pressure (IOP) in patients with primary open angle glaucoma (POAG), normal tension glaucoma (NTG) and normal subjects. Design prospective case series. The subjects were POAG, NTG patients and normal control of 30 cases. Methods The intraocular pressure (IOP) curve was measured with a Goldmann tonometer, and the intraocular pressure fluctuation patterns and peak pressure distribution were compared. The main indicators of intraocular pressure measurements. Results The peak of intraocular pressure in non-office hours was 6.7% in the right eye and 10.0% in the left eye. The NTG was 20.0% in the right eye and 23.3% in the left eye. The right eye was in the POAG. 3%, left eye 20.0%. Conclusions POAG, NTG patients and normal people have different diurnal patterns of intraocular pressure fluctuation, and the tendency of the fluctuation of both eyes are not the same. They can not be completely treated by both eyes. The peak IOP of some observers is distributed in non-office hours and many times in office hours IOP measurement can not completely replace the one day intraocular pressure monitoring. (Ophthalmology, 2007, 16: 33-36)