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目的观察固肾安胎丸联合复方黄体酮注射液治疗先兆流产的临床疗效。方法选取鼓楼区妇幼保健所2013年4月—2015年5月收治的先兆流产患者97例,根据治疗方法的不同分为对照组(n=49)和观察组(n=48),对照组单纯采用复方黄体酮注射液治疗,观察组采用固肾安胎丸联合复方黄体酮注射液治疗。比较两组患者临床治疗效果、血清人绒毛膜促性腺激素(β-HCG)及孕酮水平。结果观察组治疗总有效率为93.8%(45/48),高于对照组的77.6%(38/49),差异有统计学意义(χ~2=5.33,P<0.05)。治疗前,两组患者β-HCG、孕酮水平比较,差异无统计学意义(P>0.05)。治疗后,两组患者β-HCG、孕酮水平均高于治疗前,差异有统计学意义(P<0.05);且观察组β-HCG、孕酮水平均高于对照组,差异有统计学意义(P<0.05)。结论固肾安胎丸联合复方黄体酮注射液治疗先兆流产临床疗效明显,能够有效提高患者血清β-HCG、孕酮水平,值得临床广泛推广。
Objective To observe the clinical efficacy of Gushen AN fetal pills combined with compound progesterone injection in the treatment of threatened abortion. Methods Ninety-seven cases of threatened abortion admitted to Gulou MCH from April 2013 to May 2015 were divided into control group (n = 49) and observation group (n = 48) according to the different treatment methods. The control group Compound progesterone injection treatment, the observation group with Gushen 安胎丸 combined with compound progesterone injection. The clinical effects, serum human chorionic gonadotropin (β-HCG) and progesterone levels were compared between the two groups. Results The total effective rate of the observation group was 93.8% (45/48), which was higher than that of the control group (77.6%, 38/49). The difference was statistically significant (χ ~ 2 = 5.33, P <0.05). Before treatment, the two groups of patients with β-HCG, progesterone levels, the difference was not statistically significant (P> 0.05). After treatment, the levels of β-HCG and progesterone in both groups were significantly higher than those before treatment (P <0.05), and the levels of β-HCG and progesterone in the observation group were higher than those in the control group Significance (P <0.05). Conclusion Gushen 安fetu injection combined with compound progesterone injection clinical efficacy of threatened abortion is obvious, can effectively improve the serum levels of β-HCG, progesterone, worthy of widespread clinical promotion.