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徐叔云、陈敏珠、胡显亚等同志编著的《临床药理》(上)一书,共21讲,379,000字,是国内当前唯一的一本临床药理学专著。临床药理学,是近二十年来发展起来的一门新兴学科,它是以人体为对象,研究药物与人体之间的相互关系的一门科学,它反映了药理学和治疗学等学科密切结合下临床实践的丰富成果,对临床用药具有直接的指导作用。该书的编写确实达到了这一目的,为解决医师对常见病、多发病的合理用药和选药,起到了一定的作用。喜读之下,也发现了一些问题,现提出如下,供编著者和广大读者参考。一、个别内容前后论述不够一致(一)29页上4行:“凡弱酸性药物,如阿斯匹林……等在胃内酸性(pH 1—3)环境中,大部分为非解离状态,能通过富含类脂质的胃粘膜上皮细胞,因此在胃中吸收良好。”但29页倒11页又写道:“例如弱酸性的阿斯匹林,理论上应在胃中吸收较多,但胃排空较
The book “Clinical Pharmacology” (above) compiled by Comrades Xu Shuyun, Chen Minzhu and Hu Xianya has a total of 21 lectures and 379,000 words in total. It is the only monograph of clinical pharmacology in China. Clinical Pharmacology is a new discipline developed in the recent two decades. It is a science that studies the interrelationship between medicine and human body with the human body as the object. It reflects the close combination of pharmacology and therapeutics The rich clinical results under the guidance of clinical medication has a direct role. The book did achieve this goal, to solve the doctor’s common disease, frequently used drugs and drug selection, played a certain role. Hi reading, but also found some problems are presented below, for editors and readers reference. First, the individual content is not consistent before and after the discussion (a) 29 pages on the 4th line: “All weak acid drugs such as aspirin ... and so in the stomach acidic (pH 1-3) environment, most of the non-dissociation State, can pass through the lipid-rich gastric mucosal epithelial cells and thus absorb well in the stomach. ”But on page 29, page 11, he wrote:" For example, weakly acidic aspirin should theoretically be absorbed in the stomach More, but more gastric emptying