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[目的]了解环泰山区域是否存在恙虫病(Ot)感染。[方法]2002年9~12月,在泰山西南麓部分村庄及泰山旅游景区进行人间、鼠间Ot感染情况调查。[结果]血清抗-Ot,8例高度怀疑的现症病人均阳性(几何平均滴度为1∶320),8例既往疑似病人2例阳性,10例阳性者均为Gilliam型;血清Ot群特异基因检测,6例现症病人中4例阳性,既往病人8例中3例阳性。115名健康人群抗-Ot阳性率为8.70%,高发病村、低发病村、无发病区域分别为37.50%、10.00%、3.37%。3例急性期病人血接种小白鼠,1只肝脾肿大,Ot为阳性。捕获的16只鼠的内脏标本Ot均阴性。[结论]环泰山区域存在人间Ot感染,流行血清型为Gilliam型;尚不能排除当地存在恙虫病疫源地。
[Objective] To understand whether Otomycosis (Ot) infection exists in the Huantaishan area. [Method] From September to December, 2002, we investigated the prevalence of Ot in humans and rats in some villages in the southwestern part of Mount Tai and Taishan tourist attractions. [Results] Serum anti-Ot was positive in all the 8 highly suspected cases (geometric mean titer of 1: 320). Two of eight previously suspected patients were positive and the other ten were positive for Gilliam type. Serum Ot group Specific gene test, 6 cases of patients with positive in 4 cases, 8 cases of past patients in 3 cases were positive. The positive rate of anti-Ot in 115 healthy people was 8.70%. The high incidence village, low incidence village and non-incidence area were 37.50%, 10.00% and 3.37% respectively. Three patients with acute phase inoculation of mice, one hepatosplenomegaly, Ot positive. All the 16 mice captured were negative for Ot. [Conclusion] There was human Ot infection in Hutai Mountain region, the prevalence serotype was Gilliam type. It was not yet ruled out that there was epidemic area of scrub typhus in the area.