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[目的]分析贵州省乙型肝炎(乙肝)流行状况,寻求应对策略。[方法]采用描述流行病学方法,结合乙肝法定传染病报告数据、乙肝疫苗常规免疫接种资料进行分析。[结果]2002年以来儿童乙肝疫苗常规免疫接种率逐年提高,但首针及时率仍低。2008年全省急性乙肝年龄别发病率曲线幼年峰消失,急性乙肝发病率随年龄增加上升;遵义市、毕节地区各年龄组儿童急性乙肝发病率均高于全省。[结论]儿童乙肝疫苗常规免疫对低龄儿童已见明显的保护效果,但新生儿首针及时接种工作亟待加强,做好入学入托查证补种工作是乙肝防控的重要措施之一。遵义市、毕节地区为贵州省儿童乙肝防控的重点地区。
[Objective] To analyze the epidemic situation of Hepatitis B (Hepatitis B) in Guizhou Province and to find a coping strategy. [Methods] Descriptive epidemiological methods were used in combination with the reported data of legal infectious diseases of hepatitis B and routine immunization of hepatitis B vaccine. [Results] The routine immunization rate of children’s hepatitis B vaccine increased year by year since 2002, but the first-dose prompt rate was still low. In 2008, the peak incidence of acute hepatitis B in the province disappeared, and the incidence of acute hepatitis B increased with increasing age. The incidence of acute hepatitis B in children of all ages in Zunyi and Bijie regions was higher than that of the province. [Conclusion] The routine immunization of children with hepatitis B vaccine has obvious protective effect on young children. However, timely vaccination of neonatal needles should be strengthened. It is one of the important measures for prevention and control of Zunyi City, Bijie Prefecture of Guizhou Province for the prevention and control of hepatitis B in key areas.