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用光镜和扫描电镜技术观察了２～１０月龄人胎手指端真皮乳头嵴的形成过程。结果证实：３个月龄时真皮表面出现了原始真皮嵴，５个月龄时每条原始真皮嵴开始分化形成两条同源的真皮嵴，６个月龄时每条真皮嵴又开始分化形成许多真皮乳头，并由真皮乳头组成真皮乳头嵴，以后随胎龄的增加真皮乳头嵴逐渐增大。汗腺导管于４月龄时出现于原始真皮嵴间沟内，随着同源真皮嵴和真皮乳头嵴的形成，使汗腺导管位于两条非同源真皮乳头嵴间沟内。每条表皮嵴包被有两条非同源真皮乳头嵴。
The formation process of dermal papillary crest in finger end of 2 ~ 10 months old human fetus was observed by light microscope and scanning electron microscope. The results showed that the original dermal crest appeared on the dermis surface at 3 months of age. Each primitive dermal crest began to differentiate to form two identical dermal crests at 5 months of age. Each dermal crest began to differentiate after 6 months of age Many dermal papilla, composed of dermal papilla dermal papillae, with increasing gestational age dermal papillary crest gradually increased. Sweat gland duct at 4 months of age in the original dermal crest groove, with the homologous dermal crest and dermal papilla formation, so that the sweat duct located in two non-homologous dermal papilla intercostal groove. Each epidermal crest is covered with two non-homologous dermal papillary crests.