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在配制注射液、滴眼药时,需考虑溶液的渗透压,我们参考贾红慧等(《中成药研究》1988,(3):8)的方法,试用溶血法测定三七总提取物的氯化钠等渗当量。方法是取三七总提取物配成含皂甙浓度为3.5％的溶液进行测定。将三七总提取物溶液浓度及查到的相对应氯化钠液浓度代入以下公式计算出三七溶液的氯化钠等渗当量。
When formulating injections and eye drops, the osmotic pressure of the solution must be considered. We refer to the method of Jia Honghui et al. (“Chinese Medicine Research” 1988, (3): 8) and try hemolysis to determine the chlorination of Panax notoginseng extract. Sodium isotonic equivalent. The method is to take the total extract of Panax notoginseng and prepare a solution containing 3.5% saponin as a solution. The concentration of the total extract solution of Panax notoginseng and the corresponding concentration of the sodium chloride solution found were substituted into the following formula to calculate the isotonic equivalent of sodium chloride in the solution of Panax notoginseng.