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选择30例经胃镜检查确诊T2DM合并消化性溃疡患者,并对溃疡临床特点,发生部位及可能影响因素回顾性分析。结果:30例患者中胃溃疡18例(60%),其中,胃窦溃疡9例,胃体溃疡2例,喷门溃疡1例,胃角溃疡1例,胃角,胃窦,胃底,幽门管多发溃疡5例。十二指肠球部溃疡5例(17%),复合溃疡7例(23%),HP感染5例(17%),嗳气,返酸5例(18%),上腹不适,腹胀13例(43%),黑便1例(3%),消瘦1例(3%),恶心,呕吐7例(23%),无症状3例(10%)。结论:T2DM伴消化性溃疡患者多缺乏典型症状,溃疡发生可能与微血管和自主神经病变及口服降糖药物影响等综合因素有关,且溃疡愈合较慢。
Thirty patients diagnosed as T2DM complicated with peptic ulcer by gastroscopy were selected and the clinical features, location and possible influencing factors of ulcer were retrospectively analyzed. Results: Among the 30 patients, gastric ulcer was found in 18 cases (60%), including 9 cases of gastric ulcer, 2 cases of gastric ulcer, 1 case of squamous ulcer, 1 case of gastric ulcer and 1 case of gastric ulcer, gastric antrum, gastric fundus, Pyloric tube ulcer in 5 cases. Duodenal ulcer in 5 cases (17%), composite ulcer in 7 cases (23%), HP infection in 5 cases (17%), belching gas, acid reflux in 5 cases (18%), abdominal discomfort, abdominal distension in 13 cases (43%), one case of melena (3%), one case of emaciation (3%), nausea and vomiting in 7 cases (23%) and asymptomatic in 3 cases (10%). CONCLUSION: Most patients with T2DM complicated with peptic ulcer lack typical symptoms. The occurrence of ulcer may be related to the combined factors of microvascular and autonomic neuropathy and oral hypoglycemic drugs, and the healing of ulcer is slow.