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目的 探讨模拟失重 4周大鼠心血管调节功能和血流动力学指标变化。 方法 选体重 2 5 0~ 2 90 g的雄性大鼠2 0只随机分为悬吊组和对照组各 10只。采用尾部悬吊模拟失重大鼠模型 ,以倾斜 (HDT)和下体负压 (L BNP)实验及左心室插管方法检测立位耐力及血流动力学结果。 结果
Objective To investigate the changes of cardiovascular regulation and hemodynamics in rats after simulated weightlessness for 4 weeks. Methods Twenty male rats weighing 250-290 g were randomly divided into suspension group (n = 10) and control group (n = 10). Tail suspended simulated weightlessness rats were used to measure standing endurance and hemodynamics by using HDT and L BNP and left ventricular catheterization. Results