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目的：观察动脉化疗与栓塞治疗肾恶性肿瘤的临床与组织学疗效。方法：１９９０～１９９５年间行化疗栓塞加手术治疗（栓塞组）肾恶性肿瘤２２例，单纯手术切除（对照组）肾肿瘤２２例。对两组的手术时间、术中出血量以及术后组织学改变进行统计学分析处理。结果：（１）平均手术时间栓塞组为（９２．７±２２．９）ｍｉｎ，对照组为（１３４．５±３３．８）ｍｉｎ，（ｔ＝４．８，Ｐ＜０．００１）；术中出血量：栓塞组为（２２３±８４）ｍＬ，对照组为（４４３±１２４）ｍＬ，（ｔ＝６．９，Ｐ＜０．００１）。（２）栓塞组的组织有效率为８１．８％，与对照组（９．１％）比较差异有显著性（χ２＝１８．８，Ｐ＜０．０１）。结论：术前化疗栓塞对减少肾恶性肿瘤手术时间、术中出血量、提高组织学有效率及手术切除率均有显著的临床意义，也是中晚期肾恶性肿瘤有效的姑息治疗手段。
Objective: To observe the clinical and histological effects of arterial chemotherapy and embolization in the treatment of renal malignant tumors. Methods: Between 1990 and 1995, 22 cases of malignant neoplasm of the kidney were treated with chemoembolization plus surgery (embolization group), and 22 cases of renal tumors were resected (control group). The operation time, intraoperative blood loss and postoperative histological changes were statistically analyzed. Results: (1) The mean operative time was (92.7 ± 22.9) min in embolization group and (134.5 ± 33.8) min in control group (t = 4.8, P <0.001) Intraoperative blood loss was (223 ± 84) mL in embolism group and (443 ± 124) mL in control group (t = 6.9, P <0.001). (2) The effective rate of tissue embolization was 81.8%, which was significantly different from that of control group (χ2 = 18.8, P <0.01). Conclusions: Preoperative chemoembolization has significant clinical value in reducing the operation time of renal malignant tumor, intraoperative blood loss, improving histological efficiency and surgical resection rate. It is also an effective palliative treatment for advanced renal malignant tumors.