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目的观察洛美沙星眼药水治疗眼部细菌性疾病的疗效。方法 166例,男性91例,女性75例,年龄37a±s16a(18～65a);结膜炎92例,角膜炎74例;洛美沙星组(104例,男性54例,女性50例),用0.3洛美沙星眼药水;氧氟沙星组62例(男35例,女27例),用0.3氧氟沙星眼药水,均6次.d-1,每次1滴,7d为一个疗程;治疗前后作结膜囊分泌物或角膜刮出物培养,观察2组病例临床疗效及细菌学变化。结果洛美沙星组和氧氟沙星组总有效率分别为95.2和92(P<0.05),细菌清除率均为100,无显著不良反应。结论 0.3洛美沙星眼药水对眼部细菌性疾病有效。
Objective To observe the efficacy of lomefloxacin eye drops in the treatment of ocular bacterial diseases. METHODS: A total of 166 patients were enrolled in this study, including 91 males and 75 females, aged 37a ± s16a (18-65a), 92 conjunctivitis and 74 keratitis. Lomefloxacin group (104, 54 males and 50 females) 0.3 lomefloxacin eye drops; ofloxacin group of 62 patients (35 males and 27 females), with 0.3 ofloxacin eye drops, were 6 times.D-1, each drop of 1, 7d for a course of treatment ; Before and after treatment for conjunctival secretions or corneal scraping culture, observe the clinical efficacy and bacteriological changes in two groups. Results The total effective rates of the Lomefloxacin group and the ofloxacin group were 95.2 and 92, respectively (P <0.05), and the bacterial clearance rate was 100, with no significant adverse reactions. Conclusion 0.3 Lomefloxacin eye drops on bacterial diseases of the eye effective.