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已知人体肥胖程度与血浆胰岛素水平有密切关系。当肥胖者脂肪含量改变时,胰岛素发出信号以控制食物的摄取,维持体重的恒定。虽然平均每日血中胰岛素浓度与肥胖相关,但短暂的胰岛素水平尚受其他代谢需要的影响。循环中仅有少量胰岛素能到达中枢神经系统(CNS),然而由于有些部分脑组织不受血脑屏障的保护,可直接与循环中胰岛素接触,如下丘脑漏斗部即是实例。已经证实
It is known that the degree of human obesity is closely related to the plasma insulin level. When obese fat content changes, insulin signals to control food intake, to maintain a constant weight. Although average daily blood insulin levels are associated with obesity, transient insulin levels are influenced by other metabolic needs. Only a small amount of insulin reaches the central nervous system (CNS) in the circulation, however, since some parts of the brain tissue are not protected by the blood-brain barrier, they can directly contact with circulating insulin, for example, the hypothalamic funnel is an example. Has been confirmed