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白血病前期综合征通常骨髓均有各细胞系质和量的异常特征。临床表现为贫血、白细胞减少,外周血红细胞、白细胞及血小板异常,大多数病例血红蛋白(Hb)F增加,仅很少患者获得HbH,该综合征临床症状与体征缺乏特异性。为了对白血病前期患者作出预后的分类,作者对20例白血病前期患者作了血液学、超微结构及细胞遗传学研究,并讨论了它们之间的相关性。 20例患者中男性H6例,女性4例,55～74岁,都只作过输血治疗,并以46名血液学及临床正常的人
Pre-leukemic syndromes usually have abnormalities in the quality and quantity of each cell line in the bone marrow. Clinical manifestations of anemia, leukopenia, peripheral red blood cells, white blood cells and platelet abnormalities, most cases of hemoglobin (Hb) F increased, only few patients to obtain HbH, the syndrome of clinical symptoms and signs of lack of specificity. In order to classify the prognosis of patients with pre-leukemia, the authors performed hematological, ultrastructural and cytogenetic studies on 20 pre-leukemia patients and discussed their association. Of the 20 patients, 6 were male H, 4 were women, and 55 to 74 were transfused with only 46 hematological and clinically normal individuals