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目的:观察血液透析前后甲状旁腺激素变化,探讨常规血液透析透前与透后甲状旁腺激素变化的影响因素。方法:记录22例继发性甲状旁腺功能亢进的患者常规血液透析前后甲状旁腺激素、钙、磷等变化并计算Kt/V值。结果:常规血液透析前后甲状旁腺激素、血磷变化差异有统计学意义,血钙变化差异无统计学意义。结论:常规血液透析通过纠正高磷血症可有效降低甲状旁腺激素水平,改变血液透析方式增加血磷的充分清除亦可以有效控制甲状旁腺激素水平。
Objective: To observe the changes of parathyroid hormone before and after hemodialysis and to explore the influencing factors of parathyroid hormone before and after hemodialysis. Methods: The changes of parathyroid hormone, calcium and phosphorus before and after routine hemodialysis were recorded in 22 patients with secondary hyperparathyroidism and Kt / V values were calculated. Results: Before and after routine hemodialysis, parathyroid hormone and serum phosphorus had significant difference, but there was no significant difference in blood calcium. CONCLUSION: Conventional hemodialysis can effectively reduce parathyroid hormone by correcting hyperphosphatemia, and changing the hemodialysis method to increase the full removal of blood phosphorus can effectively control the level of parathyroid hormone.