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目的通过临床对照试验,比较汉族与维吾尔族下颌第一或第二磨牙不可复性牙髓炎患者一次性根管充填治疗术后,应用利多卡因行下牙槽神经阻滞麻醉疼痛缓解的差异,为临床针对不同患者采取个性化治疗提供依据。方法选取汉族与维吾尔族下颌第一或第二磨牙不可复性牙髓炎患者各30例,均为新疆医科大学第二附属医院口腔科2016年1—6月9:00-13:00就诊的门诊患者。在根管治疗前应用含有1∶80 000肾上腺素的利多卡因注射液5 m L,实施患侧的下牙槽神经阻滞麻醉术,之后一次性完成根管预备和根管充填。治疗结束后,嘱患者若术后感觉疼痛无法承受,遵说明书服用布洛芬缓释胶囊并记录服药剂量与时间。患者需在术后6、12、24、36、48 h利用可视化痛觉量表(VAS)记录疼痛强度,在第5天复诊时交回问卷。所得数据分别利用Mann-Whitney秩和检验、卡方检验、Cochrane Q和t检验以及Pearson correlation进行统计学分析。结果根管治疗后6、12 h,汉族患者疼痛分值明显小于维吾尔族患者(P<0.05)。维吾尔族患者术后镇痛药物的服用量也多于汉族患者(P<0.05)。结论使用利多卡因进行下牙槽神经阻滞麻醉术的下颌磨牙不可复性牙髓炎患者中,维吾尔族患者较汉族患者更容易出现术后疼痛,疼痛程度也更为剧烈,维吾尔族患者会在一次性根充治疗后,倾向于服用更大剂量的镇痛药物。
Objective To compare the differences in pain relief between patients undergoing primary root canal filling of the first and second mandibular first or second molar non-reflex pulpotomy patients in Han and Uygur nationality patients undergoing alveolar nerve block anesthesia by clinical controlled trials , Provide clinical basis for different patients to take personalized treatment. Methods Thirty patients with unrepeatable pulpitis from the first or second molars of the Han and Uygur nationalities were enrolled in this study. All patients were from the Department of Stomatology, Second Affiliated Hospital of Xinjiang Medical University from January 9 to January 13, 2016 Outpatient. Apply 5 mL of lidocaine injection containing 1:80 000 epinephrine to the root canal before anesthesia of the inferior alveolar nerve block on the affected side and complete root canal preparation and root canal filling at one time. After the treatment, Zhu Huanzhe patients feel pain after surgery, abercrombie and fitch, follow the instructions to take ibuprofen sustained release capsules and record dose and time. Patients were required to record pain intensity at 6, 12, 24, 36, and 48 h after surgery using the Visual Analogue Pain Scale (VAS) and return the questionnaire on the 5th day of referral. The data were statistically analyzed using the Mann-Whitney rank-sum test, Chi-square test, Cochrane Q-t test, and Pearson correlation, respectively. Results At 6 and 12 h after root canal treatment, the pain scores of Han patients were significantly lower than those of Uyghur patients (P <0.05). Uygur patients also took more postoperative analgesic drugs than Han patients (P <0.05). Conclusions Uygur patients are more likely to have postoperative pain and more severe pain than Uighur patients who are treated with lidocaine for mandibular molars undergoing lower alveolar nerve block anesthesia. Uyghur patients After a one-time root-filling treatment, tend to take larger doses of analgesics.