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我院自1991年1月~9月,曾于急诊室用纳洛酮(Naloxone)治疗9例急性酒精中毒。病人皆为男性,年龄20~30岁。来院前30~60min曾饮白酒250~500ml以上,其中5例兴奋、躁动、需他人予以制动;3例昏睡,对呼叫无反应;1例深度昏迷,呼吸浅且慢,大小便失禁,瞳孔中度散大,轻度发绀,对外界刺激无反应。对9例均以纳洛酮0.8mg+50%萄萄糖注射液40ml,由静脉缓慢推注(约5~10min推完)。其中8例于给药后20min完全清醒,能正确回答问题,1例深度昏迷者,亦于40min后清醒,症状、体征消除。均继续观察1h后,由家属陪伴离院。以上结果说明了应用纳洛酮治疗急性酒精中毒效
Our hospital from January 1991 to September, had emergency department with naloxone treatment of 9 cases of acute alcoholism. Patients are all men, aged 20 to 30 years. Before going to hospital 30 ~ 60min had drinking 250 ~ 500ml or more, of which 5 were excited, restless, need to be braked; 3 cases of lethargy, no response to the call; 1 case of deep coma, shallow breathing and slow incontinence, pupil Degree of dispersion, mild cyanosis, no response to external stimuli. Nine cases were naloxone 0.8mg + 50% glucose injection 40ml, slow intravenous injection (about 5 ~ 10min push finished). Eight of them were completely awake at 20 minutes after administration, and were able to answer the questions correctly. One case of deep coma was awake after 40 minutes, and the symptoms and signs were eliminated. Continue to observe 1h, accompanied by the family away. The above results illustrate the use of naloxone in the treatment of acute alcoholism