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作者证明了蟾蜍血清对梭曼中毒小鼠有解毒作用,预防效果最显著.血清酶先由静脉注入43个酶活力单位,然后于1～10h不同时间中毒,动物可100%存活.如用于治疗,则在中毒前20min先于腹腔注入阿托品10mg/kg,在梭曼皮下中毒3min后,再于静脉注入43个酶活力单位,则动物存活率为80%,而阿托品单药在1～20mg/kg范围内的不同剂量动物均死亡.当重复中毒时,先于静脉注入43个酶活力单位,每隔15min注入1LD梭曼,则动物可耐受6～7次梭曼中毒,耐受总剂量达1.2～1.4mg/kg,而97只中毒对照全部死亡.
The authors demonstrated that toad serum had a detoxification effect on soman-poisoned mice, and the preventive effect was the most remarkable. Serum enzyme was injected intravenously into 43 enzyme units and then poisoned at different times from 1 to 10 hours, and the animals could be 100% Treatment, 20 minutes before intoxication, atropine 10mg / kg prior to intraperitoneal injection, subcutaneous poisoning in soman 3min, and then in the intravenous injection of 43 units of enzyme activity, the animal survival rate was 80%, while atropine in the 1 ~ 20mg / kg range of different doses of animals were dead.When repeated poisoning, the first intravenous injection of 43 units of enzyme activity, injection of 1LD Sommer every 15min, the animals can tolerate 6 to 7 soxhmann poisoning, tolerance to total Dose of 1.2 ~ 1.4mg / kg, and 97 poisoning control all died.