论文部分内容阅读
探讨早发冠心病患者颈动脉内膜中膜厚度和斑块特征及其对早发冠心病的预测价值。应用B型超声检测早发冠心病患者颈动脉内膜中膜厚度和斑块情况 ,结合冠状动脉造影结果进行对比研究。结果发现 ,早发冠心病患者颈动脉内膜中膜厚度≥ 0 .8mm及斑块检出率明显高于对照组 (5 6 %比 11% ,P <0 .0 5 ) ;颈动脉超声阳性对预测早发冠心病的敏感性为 5 5 .7% ,特异性为 88.9% ,准确性为 87.2 % ;3支冠状动脉病变组平均内膜中膜厚度高于 1支冠状动脉病变组。多因素分析发现 ,颈动脉超声阳性是早发冠心病的独立危险因素 (OR =7.19,95 %CI:1.92～ 2 1.37,P =0 .0 0 7)。结果提示 ,早发冠心病患者颈动脉内膜中膜厚度增厚及斑块检出率升高 ,颈动脉超声阳性对诊断早发冠心病有着较高的特异性和准确性。
To investigate the carotid artery intima-media thickness and plaque characteristics in patients with premature coronary artery disease and their predictive value of premature coronary heart disease. Application of B-mode ultrasound in patients with premature coronary artery intima-media thickness and plaque, combined with coronary angiography results were compared. The results showed that carotid intima-media thickness≥0.8 mm and plaque detection rate in patients with premature coronary heart disease were significantly higher than those in the control group (56% vs 11%, P <0.05); carotid ultrasound was positive The sensitivity of predicting the risk of premature coronary heart disease was 57.7%, specificity was 88.9% and accuracy was 87.2%. The mean intima-media thickness in three coronary lesions was higher than that in one coronary artery lesion. Multivariate analysis showed that carotid artery ultrasound was an independent risk factor for premature coronary heart disease (OR = 7.19, 95% CI: 1.92-2.1737, P = 0.0007). The results suggest that carotid intima-media thickness thickening and plaque detection rate in patients with premature coronary artery disease are elevated, and carotid ultrasound positive has high specificity and accuracy in the diagnosis of premature coronary artery disease.