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目的分析2009~2010年新疆维吾尔自治区人民医院住院呼吸道感染患儿呼吸道合胞病毒(RSV)和腺病毒(ADV)感染情况和临床特征。方法采用酶联免疫吸附试验法(ELISA),对2009~2010年在新疆维吾尔自治区人民医院儿科住院的734例呼吸道感染患儿,进行血清RSV、ADV IgM抗体测定。根据检测结果,对RSV、ADV感染的季节,感染患儿的性别、年龄、民族、临床疾病及临床表现进行分析。结果 2009~2010年ADV和RSVIgM抗体全年都有检出,无明显季节性。ADV感染率24.5%(180/734),RSV感染率19.3%(142/734)。除1~3岁与>3岁组相比,两组ADV感染率有统计学差异(P<0.05)外,ADV、RSV感染在性别、年龄、民族间以及临床表现方面均无显著差异(P均>0.05)。结论 2009~2010年本地ADV和RSV感染全年流行,无明显季节性。儿科住院呼吸道感染患儿ADV和RSV感染临床表现方面无特殊,病原诊断需要实验室协诊。
Objective To analyze the prevalence and clinical characteristics of respiratory syncytial virus (RSV) and adenovirus (ADV) in hospital-acquired respiratory tract infections in People’s Hospital of Xinjiang Uyghur Autonomous Region from 2009 to 2010. Methods Serum RSV and ADV IgM antibodies were measured in 734 children with respiratory tract infection who were hospitalized in Pediatrics Department of People’s Hospital of Xinjiang Uyghur Autonomous Region from 2009 to 2010 by enzyme-linked immunosorbent assay (ELISA). According to the test results, we analyzed the season of RSV, ADV infection, sex, age, ethnicity, clinical disease and clinical manifestations of the infected children. Results 2009 ~ 2010 ADV and RSVIgM antibodies were detected throughout the year, no significant seasonal. ADV infection rate was 24.5% (180/734), RSV infection rate was 19.3% (142/734). There was no significant difference in gender, age, ethnicity and clinical manifestations between ADV and RSV infection except for 1 to 3 years of age and> 3 years of age (P <0.05) All> 0.05). Conclusion From 2009 to 2010, local ADV and RSV infections were endemic throughout the year, with no obvious seasonal changes. Pediatric inpatient respiratory tract infection ADV and RSV infection in the clinical manifestations of no special pathogen diagnosis requires laboratory co-clinic.