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目的分析鼻咽癌颈淋巴结转移的特点及鼻咽癌与颈部肿块的关系。方法对246例鼻咽癌患者的临床资料进行回顾性分析。结果246例鼻咽癌患者中有183例出现颈部肿块,其中101例为首发症状。颈部肿块位于病变同侧134例、对侧5例、双侧44例;累及颈深上淋巴结者172例。N0、N1、N2之间的EB病毒VCAIgA、EAIgA滴度水平差异无显著性;巨大颈部肿块与远处转移相关。结论鼻咽癌患者大多数会出现颈淋巴结转移,多位于病变同侧的颈深上淋巴结;EB病毒抗体滴度与颈淋巴结转移无显著相关性;巨大颈部肿块者发生远处转移可能性大。
Objective To analyze the characteristics of cervical lymph node metastasis of nasopharyngeal carcinoma and the relationship between nasopharyngeal carcinoma and cervical mass. Methods The clinical data of 246 patients with nasopharyngeal carcinoma were retrospectively analyzed. Results In 246 cases of nasopharyngeal carcinoma, 183 cases appeared cervical mass, of which 101 cases were the first symptom. Neck mass was located on the same side of the lesion in 134 cases, contralateral in 5 cases, bilateral in 44 cases; involving the deep cervical lymph nodes in 172 cases. There was no significant difference in the levels of VCAIgA and EAIgA between EBV N0, N1 and N2, and the large neck mass was associated with distant metastasis. Conclusions Most patients with NPC have cervical lymph node metastasis, mostly located in the deep cervical lymph nodes on the same side of the lesion. The antibody titer of EB virus is not significantly correlated with the metastasis of cervical lymph nodes. The possibility of distant metastasis of large neck mass is high .