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目的探讨无创经鼻正压通气治疗新生儿呼吸窘迫综合征的临床疗效。方法选取成都市郫县妇幼保健院2016年收治的呼吸窘迫综合征患儿148例,随机分为常规吸氧组与无创经鼻组,各74例。常规吸氧组患儿予以常规吸氧治疗,无创经鼻组在常规吸氧组基础上予以无创经鼻正压通气治疗。比较两组患儿临床疗效、血气分析指标[血氧分压(PaO_2)、血氧饱和度(SaO_2)]、上机时间、住院时间和住院费用。结果无创经鼻组患儿总有效率高于常规吸氧组,PaO_2、SaO_2高于常规吸氧组,上机时间、住院时间短于常规吸氧组,住院费用少于常规吸氧组(P<0.05)。结论无创经鼻正压通气治疗新生儿呼吸窘迫综合征的临床疗效确切,可有效改善患儿肺功能,缩短上机和住院时间,降低治疗费用。
Objective To investigate the clinical effect of noninvasive nasal positive pressure ventilation on neonatal respiratory distress syndrome. Methods 148 cases of respiratory distress syndrome admitted to Juxian Maternal and Child Health Hospital of Chengdu in 2016 were randomly divided into conventional oxygen inhalation group and non-invasive nasal group, 74 cases in each group. Conventional oxygen inhalation group were given conventional oxygen therapy, noninvasive nasal group in the conventional oxygen group based on non-invasive nasal positive pressure ventilation treatment. The clinical efficacy, blood gas analysis indexes (PaO_2, SaO_2), time on board, length of hospital stay and cost of hospitalization were compared between the two groups. Results The total effective rate of noninvasive nasal group was higher than that of conventional oxygen inhalation group. PaO 2 and SaO 2 were higher than those of conventional oxygen inhalation group. The time of on-boarding and hospitalization was shorter than that of conventional oxygen inhalation. <0.05). Conclusion Noninvasive nasal positive pressure ventilation is effective in treating neonatal respiratory distress syndrome, which can effectively improve the pulmonary function, shorten the time of on-boarding and hospitalization and reduce the cost of treatment.