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目的:观察银杏叶滴丸联合高压氧治疗急性一氧化碳中毒的临床疗效。方法:35例急性一氧化碳中毒患者随机分为2组。对照组17例,常规治疗(2～4周高压氧+必要的糖皮质激素+Vitc);治疗组18例,在对照组治疗基础上口服银杏叶滴丸,5粒,每天3次,服30天。对2组住院时间、入出院智能评分、神经伤残功能评分、随访迟发性脑病发病率等指标进行比较。结果:迟发性脑病发病率治疗组9.0%,对照组24.2%,2组比较,差异有显著性意义(P<0.05)。出院智能评分、神经伤残功能评分治疗组均优于对照组(P<0.05)。结论:银杏叶滴丸联合高压氧治疗能明显改善一氧化碳中毒患者高级神经功能受损,减少迟发性脑病的发生。
Objective: To observe the clinical efficacy of ginkgo leaf dropping pills combined with hyperbaric oxygen in the treatment of acute carbon monoxide poisoning. Methods: 35 patients with acute carbon monoxide poisoning were randomly divided into two groups. Control group of 17 cases, routine treatment (2 ~ 4 weeks of hyperbaric oxygen + necessary glucocorticoid + Vitc); treatment group of 18 patients in the control group based on the treatment of oral ginkgo leaf pill, 5 capsules, 3 times a day, serving 30 day. The hospitalization time, admission intelligence score, neurological disability score, follow-up incidence of delayed encephalopathy and other indicators were compared. Results: The incidence of delayed encephalopathy was 9.0% in the treatment group and 24.2% in the control group. There was significant difference between the two groups (P <0.05). Discharge intelligence scores, neurological disability score were better than the control group (P <0.05). Conclusion: Ginkgo biloba pills combined with hyperbaric oxygen therapy can significantly improve the patients with carbon monoxide poisoning impaired senior neurological function, reduce the incidence of delayed encephalopathy.